Featured Articles
Metabolite Set Enrichment Analysis (MSEA): A Comprehensive Guide for Pathway Discovery in Biomedical Research
This article provides a comprehensive guide to Metabolite Set Enrichment Analysis (MSEA), a powerful bioinformatic metho...
Targeted vs Untargeted Metabolomics: A Strategic Guide to Cross-Validation and Biomarker Workflows
This article provides a comprehensive guide for researchers and drug development professionals on implementing robust cr...
A Comprehensive LC-MS Metabolomics Protocol: From Foundational Principles to Advanced Applications and Troubleshooting
This article provides a comprehensive guide to liquid chromatography-mass spectrometry (LC-MS) metabolomics, catering to...
Indirect Calorimetry: The Gold Standard for Accurate Basal Metabolic Rate Measurement in Clinical Research and Drug Development
This article provides a comprehensive resource for researchers and drug development professionals on the application of...
Comparative Analysis of Basal Metabolic Rate Assessment Methods: From Gold Standard to Clinical Applications in Biomedical Research
This comprehensive review analyzes the accuracy, applicability, and limitations of current basal metabolic rate (BMR) as...
Emerging Biomarkers for Metabolic Syndrome and Type 2 Diabetes: From Pathophysiology to Precision Medicine
This comprehensive review synthesizes the latest advancements in biomarker science for Metabolic Syndrome (MetS) and Typ...
Genome-Scale Metabolic Model Construction: From Foundational Principles to Advanced Applications in Biomedical Research
This comprehensive review explores the evolving methodology of genome-scale metabolic model (GEM) construction, integrat...
Untargeted Metabolomics: A Comprehensive Guide to Global Metabolic Profiling in Disease Research and Drug Discovery
Untargeted metabolomics provides an unbiased, comprehensive analysis of the complete set of small-molecule metabolites i...
Lipid Biomarkers at the Crossroads: Unraveling Their Dual Role in Cancer Risk and Diabetes Pathogenesis
This comprehensive review synthesizes current research on lipid metabolism biomarkers as critical nexus points linking c...
Enzyme-Constrained Genome-Scale Metabolic Models: A Guide to Enhanced Predictions in Biomedical Research
Enzyme-constrained genome-scale metabolic models (ecGEMs) represent a significant advancement over traditional stoichiom...
13C Metabolic Flux Analysis in 3D Spheroids: Unraveling Cancer Hypoxia for Drug Discovery
This article provides a comprehensive guide for researchers on employing 13C Metabolic Flux Analysis (13C MFA) to study...
Overcoming the Hurdles: How Machine Learning is Tackling Metabolic Pathway Optimization Challenges
This article reviews the significant challenges in optimizing metabolic pathways for microbial cell factories and drug d...
Latest Articles
The Iron Paradox: How a Tiny Atom Shapes Your Health and Fights Disease
Explore the fascinating world of iron metabolism - from absorption and regulation to groundbreaking discoveries in cancer research and disease treatment.
Seeing the Unseeable: A New Window into Our Metabolic Engine
Scientists are now watching the human kidney process fuel in real-time using deuterium metabolic imaging, revealing secrets that could transform our fight again...
The Body's Double Warning: How Shape and Sugar Team Up to Predict Heart Trouble
Discover how the TyG index and Body Roundness Index combine to predict cardiovascular risk in people with abnormal glucose metabolism.
The Hunger Switch: How a Brain Protein Controls Your Metabolism
Discover how RAF1 protein in AgRP neurons regulates hunger and metabolism through the MAPK signaling pathway, with potential implications for obesity treatment.
The Cow's Sigh: How a Puff of Breath Predicts Postpartum Health
Discover how breath analysis technology is revolutionizing dairy cattle health monitoring through volatile organic compound detection.
Taming the Wine Spoiler: How UV Light Safeguards Your Pinot Noir
Discover how UV-C technology effectively controls Brettanomyces spoilage in Pinot Noir while maintaining wine stability during storage.
The Hidden Orchestra of Headache: How Painkillers Can Fuel More Pain
Exploring the molecular mechanisms behind medication overuse headache and the four key molecules that drive chronic pain cycles.
Decoding the Defenses: How Genetic Sleuthing Uncovers Brain Cancer's Treatment Resistance
Explore how genetic screening technologies are revealing the secrets behind glioblastoma's treatment resistance and opening new therapeutic avenues.
The Sugar Switch of Life: Unlocking a New Secret of Survival
Discover how the FSCN1 protein orchestrates the critical metabolic transition that enables newborn survival through hepatic gluconeogenesis.
The Hidden Heart in Your Lungs: How a Little-Known Cholesterol Might Damage Your Breathing
Discover the surprising link between remnant cholesterol and COPD risk through groundbreaking Mendelian randomization research.
The Rusting Liver: How a Tiny Molecule is Unlocking a New Path to Healing
Discover how ferroptosis, a cellular rusting process, and Ferrostatin-1 are revolutionizing liver disease treatment through groundbreaking research.
The Iron Spy: How a Radioactive Tracer Unlocked the Secrets of Digestion
Discover how radioactive Iron-59 revolutionized our understanding of iron absorption and digestion through groundbreaking scientific experiments.
Recommended Articles
Emerging Biomarkers for Metabolic Syndrome and Type 2 Diabetes: From Pathophysiology to Precision Medicine
This comprehensive review synthesizes the latest advancements in biomarker science for Metabolic Syndrome (MetS) and Type 2 Diabetes Mellitu...
Unlocking Precision Medicine: Proteomic Biomarkers for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
This article provides a comprehensive analysis of proteomic biomarkers for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD),...
Bioelectrical Impedance Analysis (BIA) in Biomedical Research: From Body Composition to Advanced Drug Screening Platforms
This article provides a comprehensive analysis of Bioelectrical Impedance Analysis (BIA) for researchers, scientists, and drug development p...
Mastering ECMpy: A Comprehensive Guide to Building and Applying Enzyme-Constrained Metabolic Models
This article provides a detailed, step-by-step guide to the ECMpy workflow for constructing and utilizing enzyme-constrained genome-scale me...
Evaluating Predictive Equations for Resting Energy Expenditure: A Comprehensive Guide for Researchers and Clinical Professionals
This article provides a systematic evaluation of predictive equations for resting energy expenditure (REE), addressing critical needs in res...
Enhancing Metabolic Model Accuracy: A Guide to Advanced kcat Prediction for ecGEMs
Enzyme-constrained genome-scale metabolic models (ecGEMs) have emerged as powerful tools for predicting cellular phenotypes, optimizing meta...
Resolving Underdetermined Systems in Flux Balance Analysis: Methods, Applications, and Validation for Biomedical Research
Flux Balance Analysis (FBA) is a cornerstone constraint-based method for modeling metabolism in systems biology and metabolic engineering.
Navigating the Data Deluge: Key Challenges and Solutions in Untargeted Mass Spectrometry Metabolomics Data Mining
Untargeted mass spectrometry metabolomics generates vast, complex datasets, presenting significant bottlenecks in data mining that hinder bi...
Decoding Cancer Metabolism: A Comprehensive Guide to 13C MFA Tracer Experiment Design for Drug Discovery
This article provides a detailed, practical guide for designing and executing 13C metabolic flux analysis (MFA) tracer experiments in cancer...
Beyond the Filter: Advanced Strategies to Mitigate Overfiltering and Preserve Biological Signal in Metabolomics
This article addresses the critical challenge of overfiltering in metabolomics statistics, a practice that can prematurely discard valuable...
Defining Metabolic Health: Biomarkers, Technologies, and Clinical Applications for Biomedical Research
This article provides a comprehensive overview of the current landscape of metabolic health parameters and biomarkers, tailored for research...
Metabolite-Metabolite Interaction Networks: From Construction to Application in Biomedical Research and Drug Discovery
This article provides a comprehensive overview of metabolite-metabolite interaction network analysis, a pivotal approach in systems biology...
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