Research Articles
NMR Lipoprotein Analysis: A Comprehensive Guide for Biomarker Discovery and Cardiovascular Risk Assessment
This article provides a detailed exploration of Nuclear Magnetic Resonance (NMR) spectroscopy for lipoprotein particle analysis, a critical tool in modern metabolic and cardiovascular research.
Beyond the Model: A Practical Guide to Genome-Scale Metabolic Model Reconstruction for Non-Model Organisms in Biomedical Research
This article provides a comprehensive, step-by-step guide for researchers and drug development professionals to build, validate, and utilize Genome-Scale Metabolic Models (GEMs) for non-model organisms.
GECKO, MOMENT, and ECMpy: A 2025 Comparative Guide for Genome-Scale Metabolic Modeling in Drug Discovery
This article provides a comprehensive analysis of three prominent genome-scale metabolic model (GEM) simulation frameworks: GECKO, MOMENT, and ECMpy.
Step-by-Step GECKO 2.0 Guide: Building Robust CRISPR Knockout Models for Drug Discovery
This comprehensive tutorial provides researchers and drug development professionals with a practical guide to constructing genetic models using the GECKO 2.0 CRISPR toolbox.
Unlocking the Polar Metabolome: A Comprehensive Guide to GC-MS Derivatization for Metabolomics Researchers
This article provides researchers, scientists, and drug development professionals with a comprehensive guide to gas chromatography-mass spectrometry (GC-MS) with derivatization for polar metabolite analysis in metabolomics.
Mastering Ethanol Quantification: A Comprehensive Guide to GC-MS/FID and HPLC Methods for Biomedical Research
This article provides researchers, scientists, and drug development professionals with a detailed, current analysis of chromatographic methods for ethanol quantification.
Volatile Metabolite Profiling: A Comprehensive Guide to Choosing Between GC-MS and LC-MS
This article provides a detailed comparison of Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for volatile metabolite profiling, tailored for researchers and drug development professionals.
GC-MS vs. LC-MS: Choosing the Right Platform for Metabolomics and Network Pharmacology
This article provides a comprehensive comparative analysis of Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for constructing metabolite interaction networks, a cornerstone of modern systems biology and drug...
Targeted Metabolomics Analysis: Choosing Between GC-MS Triple Quadrupole and Single Quadrupole for Precision Results
This comprehensive guide compares GC-MS triple quadrupole (QQQ) and single quadrupole (Q) systems for targeted metabolomics applications in biomedical research and drug development.
Rapid Quantification of Fermentation Metabolites: A Modern GC-MS Method for Researchers and Drug Developers
This article provides a comprehensive guide to developing and implementing a rapid GC-MS method for quantifying key fermentation metabolites such as acids (lactic, acetic, succinic), alcohols (ethanol, butanediol), and ketones...