Research Articles
The Arsenic Paradox: How a Deadly Poison Reveals Secrets of Metabolism and Medicine
Exploring arsenic metabolism through radioisotope 74As studies, revealing how this deadly poison functions as both toxin and medicine.
Sweet Danger: How a High-Fructose Diet Harms Both Mother and Child
Discover how maternal fructose consumption during lactation reprograms fat metabolism in both mother and child, with lasting metabolic consequences.
The Skeleton's Secret: A Missing Metabolic Link in Growing Bones
Discover how the absence of the glycerol phosphate shuttle in growth plates shapes human skeletal development and bone growth mechanisms.
Sugar, Cancer, and a Surprising Twist: The Xylitol Experiment
How a simple sugar alcohol revealed a critical weakness in liver cancer cells through metabolic reprogramming and the Warburg effect.
The Diabetes Puzzle: Can a Simple Vitamin Combat Toxic Blood Sugar?
Exploring the compelling evidence for altered thiamine metabolism in diabetes and investigating whether rational supplementation could oppose gluco- and lipotoxicity.
The Unsung Hero: How a Simple Amino Acid Helps Plants Conquer Stress
Explore how proline metabolism enables plants to withstand environmental stress and its implications for climate-resilient agriculture.
The Unseen Sculptor: How Vitamin A Remodels Your Organs on a High-Fat Diet
Discover how Vitamin A acts as a master regulator, directing how specific tissues reshape themselves in obesity through a pathway separate from mitochondrial function.
The Metabolic Masterstroke: How Ovarian Cancer Cells Rewrite Immune Cell Programming
Discover how ovarian cancer cells manipulate immune cells through N-acetylaspartate release, sustaining protumoral macrophages and creating a tumor-friendly microenvironment.
The Metabolic Price of Pressure: Unraveling Treatment Side Effects
Exploring the complex relationship between blood pressure medications and metabolic health, including side effects and emerging treatments.
The Liver's Traffic Jam: How a Common Drug Surprises Scientists
Discover how methylprednisolone and its prodrug exhibit nonlinear and sequential first-pass elimination in the liver, creating a metabolic traffic jam that challenges conventional pharmacology.