Research Articles
Metabolic Rewiring in RB-Deficient Cells: The Hidden Fuel of Cancer
Exploring how RB1 deficiency drives metabolic reprogramming in cancer cells and the therapeutic implications of targeting these vulnerabilities.
Hunting Cancer Fighters in Silicon: How Computers Are Designing Next-Generation Medicines
Explore how computational approaches are revolutionizing cancer drug discovery through in silico screening for leucine aminopeptidase inhibitors with 3,4-dihydroisoquinoline scaffold
The Cellular Tightrope: How Detached Cancer Cells Rewire Their Inner Power Grid to Survive and Spread
Discover how detached cancer cells rewire their metabolism to survive and spread, revealed through advanced 13C Flux Analysis.
A Sweet Sabotage: Starving Cancer with a Poisoned Sugar Pill
Discover how 2-Deoxy-D-glucose (2-DG) tricks cancer cells by disrupting their glycosylation process, offering a promising new approach to cancer treatment.
The Digital Hunt for Cancer's Off-Switch: How Computers are Finding New Medicines in Ancient Plants
Discover how computational biology is revolutionizing cancer drug discovery by targeting CDK2 with phytochemicals from plants.
The Unlikely Partners in Crime: How a Common Drink and a Hidden Chemical Team Up to Cause Cancer
Discover how alcohol and catechol work together with nitrosamines to dramatically increase esophageal cancer risk through groundbreaking animal research.
The Body's Betrayal: How a "Molecular Bouncer" Fuels Cancer's Drug Resistance
Exploring how P-glycoprotein expels both chemotherapy drugs and their metabolites, creating formidable cancer resistance
The Hidden World Within: How the Tumor Microenvironment Controls Cancer's Metabolism
Exploring how the tumor microenvironment controls cancer metabolism and impacts treatment effectiveness